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Official Gazette Corporate Ledger • Series 2026

Two Sigma Investments

Verified career openings and direct application dossiers for Two Sigma Investments.

Institutional Career Advisory

Open Mandates & Dossiers 48 Filings Indexed

Senior Lead Registered Nurse – ICU/Critical Care III

Two Sigma Investments • Philadelphia, PA, USA • 🇺🇸 US

$102,125 - $145,125

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Senior Lead Registered Nurse – ICU/Critical Care (Hybrid)

Two Sigma Investments • Pittsburgh, PA, USA • 🇺🇸 US

$102,125 - $145,125

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Senior Lead Senior Regulatory Affairs Specialist (FDA) III

Two Sigma Investments • Beaverton, OR, USA • 🇺🇸 US Remote Available

$154,000 - $220,000

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Senior Lead Senior Regulatory Affairs Specialist (FDA) (Hybrid)

Two Sigma Investments • Portland, OR, USA • 🇺🇸 US Remote Available

$154,000 - $220,000

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Senior Lead Senior Technical Product Manager III

Two Sigma Investments • Tempe, AZ, USA • 🇺🇸 US

$208,125 - $298,125

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Senior Lead Senior Technical Product Manager (Hybrid)

Two Sigma Investments • Scottsdale, AZ, USA • 🇺🇸 US

$208,125 - $298,125

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Senior Lead Senior Enterprise Account Executive III

Two Sigma Investments • Nashville, TN, USA • 🇺🇸 US

$172,500 - $299,000

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Senior Lead Senior Enterprise Account Executive (Hybrid)

Two Sigma Investments • Arlington, VA, USA • 🇺🇸 US

$172,500 - $299,000

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Senior Lead VP of Engineering III

Two Sigma Investments • Bethesda, MD, USA • 🇺🇸 US

$300,000 - $500,000

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Senior Lead VP of Engineering (Hybrid)

Two Sigma Investments • Washington DC, DC, USA • 🇺🇸 US

$300,000 - $500,000

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Senior Lead Senior Software Engineer III

Two Sigma Investments • Dallas, TX, USA • 🇺🇸 US

$172,000 - $247,250

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Senior Lead Senior Software Engineer (Hybrid)

Two Sigma Investments • Austin, TX, USA • 🇺🇸 US

$172,000 - $247,250

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Senior Lead Senior Growth Marketing Manager III

Two Sigma Investments • Orlando, FL, USA • 🇺🇸 US

$143,500 - $204,999

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Senior Lead Senior Growth Marketing Manager (Hybrid)

Two Sigma Investments • Miami, FL, USA • 🇺🇸 US

$143,500 - $204,999

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Senior Lead Senior Android Engineer (Kotlin) III

Two Sigma Investments • Seattle, WA, USA • 🇺🇸 US

$176,000 - $247,500

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Senior Lead Senior Android Engineer (Kotlin) (Hybrid)

Two Sigma Investments • Buffalo, NY, USA • 🇺🇸 US

$176,000 - $247,500

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Senior Lead Senior Strategy & Operations Manager III

Two Sigma Investments • Boulder, CO, USA • 🇺🇸 US Remote Available

$173,250 - $252,000

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Senior Lead Senior Strategy & Operations Manager (Hybrid)

Two Sigma Investments • Denver, CO, USA • 🇺🇸 US Remote Available

$173,250 - $252,000

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Senior Lead Senior Site Reliability Engineer III

Two Sigma Investments • Irvine, CA, USA • 🇺🇸 US

$191,250 - $270,000

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Senior Lead Senior Site Reliability Engineer (Hybrid)

Two Sigma Investments • Palo Alto, CA, USA • 🇺🇸 US

$191,250 - $270,000

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Senior Lead Staff Machine Learning Engineer III

Two Sigma Investments • San Jose, CA, USA • 🇺🇸 US Remote Available

$258,749 - $368,000

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Senior Lead Staff Machine Learning Engineer (Hybrid)

Two Sigma Investments • San Francisco, CA, USA • 🇺🇸 US Remote Available

$258,749 - $368,000

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Senior Lead Senior Reinforcement Learning Researcher III

Two Sigma Investments • Reno, NV, USA • 🇺🇸 US

$220,000 - $330,000

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Senior Lead Senior Reinforcement Learning Researcher (Hybrid)

Two Sigma Investments • Las Vegas, NV, USA • 🇺🇸 US

$220,000 - $330,000

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Senior Lead Senior Cloud Security Engineer (CSPM) III

Two Sigma Investments • Ann Arbor, MI, USA • 🇺🇸 US

$179,374 - $256,249

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Senior Lead Senior Cloud Security Engineer (CSPM) (Hybrid)

Two Sigma Investments • Detroit, MI, USA • 🇺🇸 US

$179,374 - $256,249

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Senior Lead Investment Banking Vice President III

Two Sigma Investments • Columbus, OH, USA • 🇺🇸 US

$210,000 - $367,500

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Senior Lead Investment Banking Vice President (Hybrid)

Two Sigma Investments • Durham, NC, USA • 🇺🇸 US

$210,000 - $367,500

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Senior Lead Senior FinTech Product Engineer III

Two Sigma Investments • McLean, VA, USA • 🇺🇸 US Remote Available

$179,374 - $256,249

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Senior Lead Senior FinTech Product Engineer (Hybrid)

Two Sigma Investments • Reston, VA, USA • 🇺🇸 US Remote Available

$179,374 - $256,249

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Senior Lead Principal Actuarial Analyst (ASA/FSA) III

Two Sigma Investments • Minneapolis, MN, USA • 🇺🇸 US

$168,000 - $241,500

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Senior Lead Principal Actuarial Analyst (ASA/FSA) (Hybrid)

Two Sigma Investments • Tempe, AZ, USA • 🇺🇸 US

$168,000 - $241,500

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Senior Lead Nurse Practitioner (FNP/AGPCNP) III

Two Sigma Investments • Detroit, MI, USA • 🇺🇸 US

$126,500 - $181,500

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Senior Lead Nurse Practitioner (FNP/AGPCNP) (Hybrid)

Two Sigma Investments • Cincinnati, OH, USA • 🇺🇸 US

$126,500 - $181,500

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Senior Lead Physician Assistant (PA-C) III

Two Sigma Investments • Indianapolis, IN, USA • 🇺🇸 US

$135,000 - $196,875

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Senior Lead Physician Assistant (PA-C) (Hybrid)

Two Sigma Investments • Richmond, VA, USA • 🇺🇸 US

$135,000 - $196,875

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Senior Lead Clinical Data Scientist (RWE) III

Two Sigma Investments • New York City, NY, USA • 🇺🇸 US Remote Available

$172,500 - $252,999

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Senior Lead Clinical Data Scientist (RWE) (Hybrid)

Two Sigma Investments • Irvine, CA, USA • 🇺🇸 US Remote Available

$172,500 - $252,999

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Senior Lead Medical Doctor – Hospitalist (MD/DO) III

Two Sigma Investments • Dallas, TX, USA • 🇺🇸 US

$230,000 - $380,000

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Senior Lead Medical Doctor – Hospitalist (MD/DO) (Hybrid)

Two Sigma Investments • Austin, TX, USA • 🇺🇸 US

$230,000 - $380,000

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Senior Lead Healthcare Software Architect (HL7/FHIR) III

Two Sigma Investments • Denver, CO, USA • 🇺🇸 US

$179,374 - $251,124

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Senior Lead Healthcare Software Architect (HL7/FHIR) (Hybrid)

Two Sigma Investments • Naperville, IL, USA • 🇺🇸 US

$179,374 - $251,124

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Senior Lead Director of Clinical Informatics III

Two Sigma Investments • Jacksonville, FL, USA • 🇺🇸 US

$199,500 - $283,500

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Senior Lead Director of Clinical Informatics (Hybrid)

Two Sigma Investments • Tampa, FL, USA • 🇺🇸 US

$199,500 - $283,500

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Senior Lead Bioinformatics Engineer (Genomics Pipeline) III

Two Sigma Investments • Memphis, TN, USA • 🇺🇸 US

$166,625 - $241,875

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Senior Lead Bioinformatics Engineer (Genomics Pipeline) (Hybrid)

Two Sigma Investments • Nashville, TN, USA • 🇺🇸 US

$166,625 - $241,875

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Senior Lead Pharmacy Director (PharmD) III

Two Sigma Investments • Durham, NC, USA • 🇺🇸 US

$163,125 - $236,250

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Senior Lead Pharmacy Director (PharmD) (Hybrid)

Two Sigma Investments • Raleigh, NC, USA • 🇺🇸 US

$163,125 - $236,250

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